Correction: A novel Prins cascade process for the stereoselective synthesis of oxa-bicycles.

نویسندگان

  • B V Subba Reddy
  • A Venkateswarlu
  • B Sridevi
  • Kanakaraju Marumudi
  • A C Kunwar
  • G Gayatri
چکیده

E- and Z-9-Methyldeca-3,8-dien-1-ols undergo smooth cyclization with aldehydes in the presence of 20 mol% AgSbF6 under extremely mild conditions to generate the corresponding oxa-bicycles in good yields with excellent selectivity. In fact, E-olefin affords the trans-product exclusively, whereas the Z-olefin gives the cis-product predominantly. In the case of E- or Z-8-methylnona-3,8-dien-1-ol, the product is formed via the termination of Prins cyclization with an allylic C-H bond through olefin migration. The termination of Prins cyclization with tethered olefin is an unprecedented reaction, which provides a useful motif of various natural products.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 14  شماره 

صفحات  -

تاریخ انتشار 2015